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Niacinamide: Its Benefits and Uses

Updated: Mar 15


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Niacinamide, or Nicotinamide, is a form of vitamin B3 that has gained significant attention in the beauty and skincare industry. It is water-soluble, meaning it does not get stored in the body and must be replenished through diet, supplements, or skincare products. Renowned for its versatility and gentle nature, Niacinamide is celebrated for its ability to improve skin health, even out skin tone, and support overall cellular function.


What is Niacinamide?

Niacinamide is a water-soluble form of vitamin B3, essential for maintaining healthy skin and overall bodily functions. Unlike niacin (nicotinic acid), Niacinamide is less likely to cause side effects like flushing, making it a popular choice for skincare formulations. It plays a critical role in cellular energy production, supports the skin’s barrier, and helps regulate inflammation, making it a key ingredient in addressing various skin concerns.


The Benefits of Niacinamide


For the Skin:

  1. Reduces Inflammation: Niacinamide helps calm redness and irritation, making it ideal for people with acne, rosacea, or sensitive skin.

  2. Controls Oil Production: It helps regulate sebum (oil) production, reducing excess shine and preventing clogged pores.

  3. Minimizes Pores: With regular use, niacinamide can refine the appearance of pores, giving skin a smoother look.

  4. Evens Skin Tone: It reduces hyperpigmentation, dark spots, and redness, leading to a more uniform complexion.

  5. Boosts Hydration: Niacinamide strengthens the skin barrier, preventing moisture loss and improving overall hydration.

  6. Fights Signs of Aging: It stimulates collagen production, reducing the appearance of fine lines and wrinkles.

  7. Protects Against Environmental Damage: As an antioxidant, it helps defend against UV damage and pollution.


For Overall Health:

  1. Supports Brain Function: Niacinamide plays a role in brain health and has been studied for its potential benefits in neurological conditions like Alzheimer’s disease.

  2. Enhances Energy Production: It aids in converting food into energy, helping maintain overall vitality.

  3. Boosts Immune Function: It supports the immune system and has anti-inflammatory properties.


Who Should Use Niacinamide?

Niacinamide is suitable for almost all skin types due to its gentle, non-irritating properties. It is particularly beneficial for:


  • People with acne-prone or oily skin

  • Those struggling with hyperpigmentation or uneven skin tone

  • Individuals with dry or sensitive skin needing barrier repair

  • Those looking to prevent or reduce fine lines and wrinkles

  • Anyone exposed to environmental stressors like pollution and UV rays


Since niacinamide is well-tolerated, even individuals with sensitive skin can typically use it without irritation.


How to Use Niacinamide and How Often

Niacinamide is available in various formulations, including serums, creams, lotions, and even supplements. Here’s how to incorporate it into your routine:


Topical Use in Skincare:

  • Serums & Moisturizers: Niacinamide is commonly found in serums and moisturizers with concentrations ranging from 2% to 10%.

  • How Often to Use: It can be used once or twice daily, morning and night.

  • Application Order: Apply after cleansing and toning but before heavier creams and oils. If using a serum, follow up with a moisturizer and sunscreen in the morning.


For most users, applying niacinamide once or twice daily is effective. If you're new to the ingredient, start with a lower concentration and gradually increase usage as your skin adapts.


Supplement Use:

  • Niacinamide supplements are available in capsule or tablet form, typically ranging from 100 mg to 500 mg per dose.

  • Recommended doses vary based on individual needs and medical advice.

  • Consult a doctor before starting niacinamide supplements, especially at high doses.


Topical vs. Supplement Use: Which One is Better?

Aspect

Topical Niacinamide

Niacinamide Supplements

Purpose

Targets skin concerns directly

Supports overall health and skin from within

Speed of Results

Faster, visible in 4-8 weeks

Slower, systemic benefits over time

Best For

Acne, ageing, hyperpigmentation, hydration

Energy production, brain health, and immune function

Side Effects

Minimal, mild irritation in rare cases

High doses may cause nausea, liver issues, or flushing

If your primary goal is improving your skin, topical niacinamide is the best choice. If you’re looking for overall health benefits, supplements may be more beneficial.


Mixing Niacinamide with Other Ingredients

Niacinamide is known for its compatibility with a variety of skincare ingredients. Here are some effective combinations:


  • Hyaluronic Acid: When used with hyaluronic acid, niacinamide helps boost hydration and maintain a plump, dewy complexion.

  • Vitamin C: Recent studies suggest that niacinamide and vitamin C can be used together effectively. This combination offers powerful antioxidant protection and brightening effects, though it’s best to ensure the formulation is pH-balanced.

  • Peptides: For enhanced anti-ageing benefits, pair niacinamide with peptides to support collagen synthesis and improve skin firmness.

  • Retinol: To mitigate retinol-induced irritation, niacinamide can be layered before or after retinol products, providing soothing benefits and maintaining the skin barrier.

  • Zinc: In formulations for acne-prone skin, zinc and niacinamide work together to reduce inflammation and regulate sebum production.

  • Salicylic Acid: Works well for acne-prone skin, reducing oil and breakouts.


Ingredients to Be Cautious With:

  • Strong Exfoliants (AHAs/BHAs): Using high concentrations of exfoliating acids alongside niacinamide may increase sensitivity.

  • High-Dose Niacinamide (Over 10%): Can sometimes cause irritation or redness in sensitive skin.


When mixing Niacinamide with other actives, it’s important to introduce new products gradually and perform a patch test to avoid potential irritation.


Potential Side Effects of Niacinamide


Topical Niacinamide:

  • Generally well-tolerated, but some may experience mild redness, irritation, or itching—especially with high concentrations (10% or more).

  • If irritation occurs, start with a lower concentration (2-5%) and gradually increase.


Niacinamide Supplements:

  • Safe in recommended doses, but excessive intake (over 500 mg daily) may cause:

    • Flushing: A temporary warm, red sensation on the skin.

    • Nausea or Stomach Discomfort: If taken on an empty stomach.

    • Liver Issues: At very high doses (above 3,000 mg per day).


Tip: Always consult a doctor before taking high-dose niacinamide supplements.



 


Niacinamide is a powerhouse ingredient with impressive benefits for both skin health and overall wellness. Whether applied topically or taken as a supplement, it offers anti-ageing, anti-inflammatory, and skin-brightening properties. It is suitable for all skin types, pairs well with most skincare ingredients, and has minimal side effects when used correctly.

For those looking to improve their skin, incorporating a niacinamide serum or moisturizer into a daily routine is a great choice. If you're seeking broader health benefits, consider dietary sources or supplements under medical guidance.

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